Berberine, a naturally occurring isoquinoline alkaloid form Rhizoma coptidis, is widely used in China as a folk medicine for its antibacterial and anti-inflammatory properties. Vascular diseases affecting vasculature in the heart, cerebrovascular disease, atherosclerosis, and diabetic complications have compromised quality of life for affected individuals and increase the burden on health care services. Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications. 4Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.3School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
2Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.1School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.Xiaopeng Ai 1,2, Peiling Yu 2, Lixia Peng 1, Liuling Luo 1, Jia Liu 3, Shengqian Li 2, Xianrong Lai 1,3, Fei Luan 1* and Xianli Meng 1,4*
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